If there wasn't either statistical information or innate sense ("conventional wisdom" or "hitting psychology") to maximize the production of a given batting order, then the simple solution would be to arrange your hitters , with sufficient sample size, in descending order of OB% because the guys who are better at getting on base will bat more often, up to 150-170 times more than the lesser OBP'ers, over the course of the season. Yet no one does this .
I think S5Dewey's note above regarding the numerous variables, particularly the pitcher's reactions and defensive decisions, to situations affects outcomes as much as any one thing the hitter/runner tries to do. And if you don't think perception (psychological factors) come into play by both the hitter and pitcher, you haven't been on the mound and seen Big Papi in the on deck circle .