We know the Sox value continuity, they don't want to make a guy learn a new position and learn how to be a big leaguer at the same time.
They most certainly would not do that at the same time a kid who is not even 2 months into his mlb career is struggling and trying to figure out how to make adjustments. They want him to work through this, they obviously have a lot of faith in him evidence by the contract extension they gave him. They're not going to eff that up by moving him to 1B. And they shouldn't.
Mayer is one of baseballs top prospects projected to be an above average ss for years to come. Any talk about moving him there (and breaking him into the majors) is also just not going to happen.
I suppose these things could happen, it's not 100% out of the realm of possibility, but it's highly unlikely.
Unfortunately if Devers does not want to move, you're going to have to go out and find someone to plug the hole.
Sox should kick the tires with Baltimore on Ryan O'Hearn