It is not misery nor giving up after a single game. The Sox will win at least 70, and maybe up to 90. It is watching poorly executed baseball in all 3 categories plus lack of a running game , that as mentioned above extends back to the last two weeks of ST and through yesterday. Cora's teams, IMO, are never quite mentally ready to consistently play at a smart level.
Having said that you can point to 2021's start with the 3 games lost to the same O's for encouragement. Trouble is trash ball like we saw should'nt be the standard we bring to a season opener. The hometown edge was quickly wasted with plenty of booing.