For minor leaguers in A ball, 2022 is not "near horizon". Especially for those not playing in 2020.
you listed 29 minor leaguers, all but 7 of whom have never played above A ball, and one of those 7 (Downs) has 12 games at that level. How many actual major leaguers do you think are in that crowd? The bulk of them will never never get out of AA ball, assuming they get there at all.
Now that does not mean they are useless. The Sox will deal a few hopefully, for actual MLB talent.
But by 2022, out of that list of 29, I would suspect the only ones to actually play in MLB would be Dalbec, Mata, Duran, Houck, and maybe Wilson.