Let's assume Kelly, Romy & Casas begin the year on the IL or in AAA, our 26 man roster would have 10 players who did not play a single game for the Sox in 2025:
Suarez, Gray, Oviedo, Crawford, Sandoval, Watson (+Moran w 4 IP)
Contreras, Durbin, Kiner-Falefa & Monasterio
The AAA roster has at least 17 players new to the system:
Sikkema, Gamboa, Samaniego, Berrios, Sweet, Martinez, T Guerrero, Nittoli, K Keller
Gasper, Thaiss, Rodgers, Cheng, Ward, Lloyd, Seigler, Capra, Frazier