No its not. Its a no brainer if Loretta bunts the guys to second and third. In that case, with guys on 2nd and 3rd you set up a force play by walking him, keep the double play intact, etc., Loading the bases AND moving the runners up a base means that Manny simply needs a single to tie the game. Odds are that Manny will get a hit more often than Papi will get a homerun, ergo, pitch to Papi.
Over, and over and over again. That's why everyone keeps talking about Manny as being the glue that holds the Sox lineup together. The guy has a 1.000+ OPS and a .430 OBP. They will avoid Manny till the cows come home.