It's meaningful but not everything and likely not a major factor.
The Yanks have shown over and over, they fall flat right after looking unbeatable. plus, they have a manger prone to handing games away.
It's one game. lots of factors are involved, including home field, starting pitchers and head-to-head pitcher-batter match-ups.
We don't even know, if it will be Cole vs Sale or Eovaldi, and SP'er is usually the biggest factor in setting odds on winning.
If the Yanks clinch early and can set up their SP'er and rest their pen, I'd have to give them the edge, but with the jays and Rays left to play, that is far from a given with a 1 game lead on us.
Here's how their pitchers likely line up
Off
@TOR Taillon v Ryu
@TOR Cole v Berrios
@TOR Kluber v RRay
vTBR Montgomery
vTBR Cortes
vTBR Cole on short rest, if needed (Taillon, if not)