From the Globe:
SEATTLE - Sox first baseman Kevin Youkilis was scratched from tonight's lineup because of a pain in the top of his right hand. Youkilis said he doesn't remember how he hurt the hand, but he decided he couldn't play after taking batting practice.
The injury, which Youkilis said he started feeling last night, is day-to-day.
As a result, Youkilis, who was going to bat sixth, was replaced at first base by Sean Casey, who bats eighth. J.D. Drew is now hitting sixth, Varitek seventh, Casey eighth, and Lugo ninth.