Cora has been known to stick with a lineup that works. This year he's had a bunch of lefty bats--Devers, Verdugo, Casas, Duran, McGuire, Yoshida, Valdez, etc--and the Sox have naturally faced a lot of righty starters. So five (Devers, Dugo, Casas, Duran, and Yoshida) of the lefty hitters are in the top seven (of Sox batters) in at bats. The three righty bats in the top eight of at bats are Turner, Kike, and Wong.
Rookies Duran and Casas are the ones most likely to be replaced in the lineup against a lefty starter.