I do like it. I get so bored of playing the same 4 teams 72 times a year. I would love to get the chance to see players like Pujols and Josh Johnson, and Tim Lincecum play instead of Guthrie and Dan Fuld.
However, the way the MLB deals with it is absolutely retarded. I do not use that word lightly, but the simple fact is that it creates a significant unfair advantage for some teams, and not others. There is simply no other word to describe the idiocy of the way it is handled. On top of that, how many AL pitchers hurt themselves while batting during interleague play? I really enjoy interleague play, but some consistency would make it a lot easier for devoted fans to get into it.