Jacko, Corey Webster will play at the other corner along with Aaron Ross.
As for making up for Strahan, a lot of that will depend on how healthy and effective Kiwanuka is. Before he got hurt he was showing significant improvement at linebacker, but his biggest strength is rushing the passer (whether it is from the linebacker position or as a linemen). I know Strahan is great, and it would be impossible to completely replace him, but what they lost with him they hope to gain with having a healthy Kiwanuka. And, of course, this gives Justin Tuck the opportunity to play every down.
As for the offense, losing Shockey will probably hurt, but I do like Kevin Boss. He's not Shockey, but he's a big target for Eli with really good hands. But I think the biggest strength of the offense will be on the ground. The trio of Brandon Jacobs, Ahmad Bradshaw, and Derrick Ward has the potential to be deadly if they are all used correctly. But obviously, the offense goes as Eli goes and the big question is whether he has completely turned the corner.