Kluber, Ort and Mondesi are on the 60 day IL, so they do not take up a roster slot. They are as good as DFA'd, and will be let go.
To me, even with no outside additions, the addition of Rule 5 players will take all the slots of the 60 man IL guys, which would leave these guys to be replaced with outside the system additions:
Jacques, Barraclough, Garza, Weiss>
SP1
SP2
SP4
LH'd RP
Then, can Llovera or Gillaspie for a RH'd power bat who can play plus D in CF or RF.
The 40 man might be stuck with one guy like Dalbec, but we could just protect one more rule 5 guy and trade him, too.