I already posted career numbers with RISP, but if you really only want to talk about recent performance, here are the 2009 season numbers:
2009 RISP:
Cano: 0.207 BA, 0.242 OBP, 0.332 SLG, 0.574 OPS in 198 PA
Pedroia:0.327 BA, 0.418 OBP, 0.440 SLG, 0.858 OPS in 185 PA
Cano is the 5 hitter and he gives them no production when it counts. Pedroia is the #2 hitter and does his job perfectly, but unlike Cano, he actually produces when it matters most. Thus, I take Pedroia over Cano.