This is a 162 game season and pitchers in particular feel a lot of wear and tear going through it, not to mention outright injuries. Pitchers throw harder on average than in the past and while a lot of guys are big, nevertheless, they still feel worn down. In the case of the Sox, we have had a lot of outings where the starter goes 5 innings and sometimes less, meaning the bullpen gets worked very hard. Cora has tried to mitigate the wear and tear but it is still there for the Sox and every other team.
We are hoping that guys like Sale and E-Rod and to some extent Price will have been rested enough to bring them into the Playoffs in decent form. Remember in Spring Training next year, this kind of baseball wear factor will very much come into play again next year.