I don't exactly see why the situations aren't comparable. They are not the same, but they are similar in that both teams have a lot of money invested in high priced talent that may or may not deliver. The Cubs were probably worse off, but not that much worse.
I only see 4 players meaningfully coming off the books next year: Papi, Youk, Dice, Jenks. Youk has an option. If none of them come back, then that's $43 million in capacity. However, I don't see a lot of cheap talent to step in and replace that production right away, plus we may need more than a DH and 3B during the off-season. So the team may choose to replenish the farm at the ASB this year by trading some players with value for prospects.
It makes a lot of sense if you're not going to make the playoffs in 2012 to trade away a Lester, Buchholz, Ellsbury, etc. if you can get top prospects back.