Yes. I don't think they have any pitchers that remotely scare me, outside of Francis and Corpas. Fuentes is VERY hittable and their 7th inning guy is LaTroy Hawkins. That should tell you something. As for their rotation, I feel Jiemenez is too wild and prone to the long ball. Yeah, he could spin a gem, but I think the Sox's patience will wear him down. Fogg/Cook are "meh". The guy who could be tough is Morales, being a rookie pitcher and left-handed. But that's not enough to convince me we won't hit him.
The layoff will hurt more than it will help. They have a good lineup...but is it better than ours?
C - Varitek/Torrealba - Push, maybe slight edge to Colorado.
1B - Youkilis/Helton - Right now, it'd be advantage Youkilis. Over the season, Helton. Call it a push.
2B - Pedroia/Matsui - Edge Pedroia.
SS - Tulowitzki/Lugo - Edge Tulo
3B - Lowell/Atkins - Edge Lowell b/c of Atkins' road split
RF - Drew/Hawpe - Right now, advantage Drew
CF - Ellsbury/Taveras - Push
LF - Ramirez/Holliday - Slight Edge to Ramirez
DH - Ortiz/Spilborghs - Huge edge to Ortiz
All in all, lots of similarities. I'd take our top 5 right now (Ortiz, Ramirez, Lowell, Youkilis, Pedroia) over their top 5 (Holliday, Helton, Tulowitzki, Hawpe, Atkins).