I'll give it a shot...
1. Coco Crisp, CF
2. Mark Loretta, 2b
3. David Ortiz, DH
4. Manny Ramirez, LF
5. Mike Lowell, 3b
6. Trot Nixon/Wily Mo Pena, RF
7. Jason Varitek, C
8. Kevin Youkilis, 1b
9. Alex Gonzalez/Alex Cora, SS
Once Coco gets back I'd really like to see Lowell in the 5 spot, I think he's dangerous enough to protect Manny. Varitek needs to be dropped down a bit due to his struggles.
Youkilis batting 8th provides a LOT of depth.