Front offices can mess up a guy's career by overmanaging. In the Red Sox case, it's possible to say moving Bard to starter messed him up, especially when he had a history of such problems in the minors--why he was moved to reliever in the first place. Further, others have suggested that Dice-K's routine in Japan may have been messed up when he came to Boston. The Red Sox seem to have well cast ideas about how to condition pitchers--or at least did then, regarding pitch counts, in particular. Maybe less so, now. I've read the whole pitch count philosophy is being reexamined in Baseball. I've often thought it was misused.
It has never made any sense to me to take out a starter cruising in a quality start just because he reached some magical pre-set number of pitches. I've read about some major pitchers lately taking issue with just that. Last year, Farrell showed some awareness of this, and was flexible at times with pitch counts.
Another area that concerns me is moving guys around positions at the major league level like musical chairs. That can mess up a guy, too. Especially if he's a younger guy who hasn't fully developed his confidence at the ML level. That's an argument not to shuffle X or Middlebrooks around to accommodate Drew--a one position guy who will be paid big to start. Maybe that's one of his problems finding a taker--along with the draft pick.